Chemical and Pharmaceutical Bulletin
The Pharmaceutical Society of Japan, established in 1880, is one of Japan’s oldest and most distinguished academic societies. The Society currently has around 18,000 members. It publishes three monthly scientific journals. Chemical and Pharmaceutical Bulletin (Chem. Pharm. Bull.) began publication in 1953 as Pharmaceutical Bulletin. It covers chemistry fields in the pharmaceutical and health sciences. Biological and Pharmaceutical Bulletin (Biol. Pharm. Bull.) began publication in 1978 as the Journal of Pharmacobio-Dynamics. It covers various biological topics in the pharmaceutical and health sciences. A fourth Society journal, the Journal of Health Science, was merged with Biol. Pharm. Bull. in 2012. Yakugaku Zasshi (Japanese for “Pharmaceutical Science Journal”) has the longest history, with publication beginning in 1881. Yakugaku Zasshi is published mostly in Japanese, except for some articles related to clinical pharmacy and pharmaceutical education, which are published in English.
The main aim of the Society’s journals is to advance the pharmaceutical sciences with research reports, information exchange, and high-quality discussion. The average review time for articles submitted to the journals is around one month for first decision. The complete texts of all of the Society’s journals can be freely accessed through J-STAGE. The Society’s editorial committee hopes that the content of its journals will be useful to your research, and also invites you to submit your own work to the journals.

Chairman of Committee
Naoto Oku
School of Pharmaceutical Sciences, University of Shizuoka



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26,928 registered articles
(updated on March 30, 2017)
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Volume 65 (2017) Issue 3 Pages 268-275
Adsorption Capability of Cationic Dyes (Methylene Blue and Crystal Violet) onto Poly-γ-glutamic Acid

In this study, the adsorption capability of cationic dyes, which were methylene blue and crystal violet, by poly-γ-glutamic acid (PGA) in a single or binary solution system was investigated. The effect of the molecular weight of PGA, initial dye concentration, solution pH, and temperature on the adsorption of dyes was evaluated. The adsorption mechanism of dyes onto PGA was the interaction between –COOH group on the PGA surface and the polarity groups of dyes. These results indicated that PGA is useful for removal of dyes and cationic organic compounds from a single or binary solution system.

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In this paper, the adsorption capacity of methylene blue (MB) and crystal violet (CV) to poly-γ-glutamic acid (PGA) is described. PGA contained in natto (Japanese traditional fermented food) is a homopolyamide having bonds between α-amino and γ-carboxy groups of D- and L-glutamic acid monomers. The removal rate of MB or CV by PGA was 94.6 to 100% after 120 min. In addition, PGA has a dye adsorption capacity in a binary solution system. The results of this study indicate that PGA is useful for removing dyes from aqueous solutions.



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  • Chem. Pharm. Bull. Vol. 65 No. 4(Coming soon)
    Current Topics: Cutting-edge Science of Cyclodextrin


  • Chem. Pharm. Bull. Vol. 65 No. 1
    Current Topics: Reversal or Control of the Innate Reactivity of Functional groups




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